RPL35 ist ein Gen, das durch das Symbol RPL35 kodiert wird. Es ist auch bekannt als: 60S ribosomal protein L35; Large ribosomal subunit protein uL29. RPL35 hat eine Masse von 14.55kDa, eine Aminosäurelänge von 123, und ist an Diamond-Blackfan anemia 19 beteiligt.
Wir bieten 6 antikörper gegen RPL35, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Component of the large ribosomal subunit.
Entrez Zusammenfassung
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Rolle bei Krankheiten
Diamond-Blackfan anemia 19: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. DBA19 inheritance is autosomal dominant.
Sequenzähnlichkeiten
Belongs to the universal ribosomal protein uL29 family.
