RhD ist ein Gen, das durch das Symbol RHD kodiert wird. Es ist auch bekannt als: Blood group Rh(D) polypeptide; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen. RhD hat eine Masse von 45.21kDa und eine Aminosäurelänge von 417.
Wir bieten 6 antikörper gegen RhD, aufgewachsen in Kaninchen und Human, welche geeignet sind für WB and ELISA mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Entrez Zusammenfassung
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.
Gewebespezifität
Restricted to tissues or cell lines expressing erythroid characters.
Sequenzähnlichkeiten
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Posttranslationale Modifikation
Palmitoylated.
