RAP2C ist ein Gen, das durch das Symbol RAP2C kodiert wird. Es ist auch bekannt als Ras-related protein Rap-2c. RAP2C hat eine Masse von 20.75kDa und eine Aminosäurelänge von 183.
Wir bieten 3 antikörper gegen RAP2C, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC and ELISA mit Proben abgeleitet von Human und Maus.
Gen- und Proteininformationen
UniProt Zusammenfassung
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.
Entrez Zusammenfassung
The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants.
Gewebespezifität
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.
Sequenzähnlichkeiten
Belongs to the small GTPase superfamily. Ras family.
Posttranslationale Modifikation
Palmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK.
Zellort
Cytoplasm. Recycling endosome membrane.
