Perilipin 3 ist ein Gen, das durch das Symbol PLIN3 kodiert wird. Im Allgemeinen auch bezeichnet als: Perilipin-3; 47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; Cargo selection protein TIP47; Mannose-6-phosphate receptor-binding protein 1; Placental protein 17; PP17; PLIN3; M6PRBP1; TIP47. Perilipin 3 hat eine Masse von 47.08kDa und eine Aminosäurelänge von 434.
Wir bieten 5 antikörper gegen Perilipin 3, aufgewachsen in Kaninchen und Ziege, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
Entrez Zusammenfassung
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.
Sequenzähnlichkeiten
Belongs to the perilipin family.
Zellort
Cytoplasm. Endosome membrane. Lipid droplet.
Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails.
