NQO2 ist ein Gen, das durch das Symbol NQO2 kodiert wird. Im Allgemeinen auch bezeichnet als: Ribosyldihydronicotinamide dehydrogenase [quinone]; NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2; NMOR2. NQO2 hat eine Masse von 25.92kDa und eine Aminosäurelänge von 231.
Wir bieten 7 antikörper gegen NQO2, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus, Ratte, Affe und Hund.
Gen- und Proteininformationen
UniProt Zusammenfassung
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Entrez Zusammenfassung
This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.
Sequenzähnlichkeiten
Belongs to the NAD(P)H dehydrogenase (quinone) family.
