Noelin ist ein Gen, das durch das Symbol OLFM1 kodiert wird. Im Allgemeinen auch bezeichnet als: Neuronal olfactomedin-related ER localized protein; Olfactomedin-1; OLFM1; NOE1; NOEL1. Noelin hat eine Masse von 55.34kDa und eine Aminosäurelänge von 485.
Wir bieten 10 antikörper gegen Noelin, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC and ELISA mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli (By similarity).
Entrez Zusammenfassung
This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene.
Zellort
Secreted. Cell junction > Synapse. Endoplasmic reticulum. Cell projection > Axon. Perikaryon.