Muscarinic Acetylcholine Receptor 1 ist ein Gen, das durch das Symbol CHRM1 kodiert wird. Im Allgemeinen auch bezeichnet als: Muscarinic acetylcholine receptor M1; CHRM1. Muscarinic Acetylcholine Receptor 1 hat eine Masse von 51.42kDa und eine Aminosäurelänge von 460.
Wir bieten 6 antikörper gegen Muscarinic Acetylcholine Receptor 1, aufgewachsen in Kaninchen und Ziege, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Entrez Zusammenfassung
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Sequenzähnlichkeiten
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM1 sub-subfamily.
Zellort
Cell membrane. Cell junction > Synapse > Postsynaptic cell membrane.
