Mannose Receptor ist ein Gen, das durch das Symbol MRC1 kodiert wird. Im Allgemeinen auch bezeichnet als: Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human hMR; Macrophage mannose receptor 1-like protein 1; MRC1; CLEC13D; CLEC13DL; MRC1L1. Mannose Receptor hat eine Masse von 166.01kDa und eine Aminosäurelänge von 1456.
Wir bieten 18 antikörper gegen Mannose Receptor, aufgewachsen in Kaninchen, Maus und Ratte, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC and IP mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.
Entrez Zusammenfassung
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Zellort
Endosome membrane. Cell membrane.