IL5 ist ein Gen, das durch das Symbol IL5 kodiert wird. Im Allgemeinen auch bezeichnet als: Interleukin-5; IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF. IL5 hat eine Masse von 15.24kDa und eine Aminosäurelänge von 134.
Wir bieten 25 antikörper gegen IL5, aufgewachsen in Kaninchen, Maus, Ratte und Human, welche geeignet sind für WB, IHC, ELISA and FC mit Proben abgeleitet von Human, Maus, Ratte, Rind, Schwein, Schaf, Goat, Meerschweinchen und Primaten.
Gen- und Proteininformationen
UniProt Zusammenfassung
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Entrez Zusammenfassung
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Sequenzähnlichkeiten
Belongs to the IL-5 family.
