ICAM2 ist ein Gen, das durch das Symbol ICAM2 kodiert wird. Im Allgemeinen auch bezeichnet als: Intercellular adhesion molecule 2; ICAM-2. ICAM2 hat eine Masse von 30.65kDa und eine Aminosäurelänge von 275.
Wir bieten 15 antikörper gegen ICAM2, aufgewachsen in Kaninchen, Maus und Ratte, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC and IP mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Entrez Zusammenfassung
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Sequenzähnlichkeiten
Belongs to the immunoglobulin superfamily. ICAM family.
Zellort
Membrane. Cell projection > Microvillus.
Co-localizes with RDX, EZR and MSN in microvilli.
