GM-CSF Receptor alpha ist ein Gen, das durch das Symbol CSF2RA kodiert wird. Im Allgemeinen auch bezeichnet als: Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GM-CSF-R-alpha; CDw116; CSF2RA; CSF2R; CSF2RY. GM-CSF Receptor alpha hat eine Masse von 46.21kDa, eine Aminosäurelänge von 400, und ist an Pulmonary surfactant metabolism dysfunction 4 beteiligt.
Wir bieten 13 antikörper gegen GM-CSF Receptor alpha, aufgewachsen in Kaninchen, Maus und Human, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC and IP mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Entrez Zusammenfassung
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
Rolle bei Krankheiten
Pulmonary surfactant metabolism dysfunction 4: A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
Sequenzähnlichkeiten
Belongs to the type I cytokine receptor family. Type 5 subfamily.
