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Anti-GAD67 Antikörper

16 Products

GAD67 ist ein Gen, das durch das Symbol GAD1 kodiert wird. Im Allgemeinen auch bezeichnet als: Glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform; GAD1; GAD. GAD67 hat eine Masse von 66.9kDa, eine Aminosäurelänge von 594, und ist an Cerebral palsy, spastic quadriplegic 1 beteiligt.

Wir bieten 16 antikörper gegen GAD67, aufgewachsen in Kaninchen, Maus und Ziege, welche geeignet sind für WB, IHC, ELISA, ICC/IF and FC mit Proben abgeleitet von Human, Maus und Ratte.

Gen- und Proteininformationen

UniProt Zusammenfassung
Catalyzes the production of GABA.
Entrez Zusammenfassung
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Gewebespezifität
Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain.
Rolle bei Krankheiten
Cerebral palsy, spastic quadriplegic 1: A non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest symmetrical, non-progressive spasticity and no adverse perinatal history or obvious underlying alternative diagnosis. Developmental delay, mental retardation and sometimes epilepsy can be part of the clinical picture.
Sequenzähnlichkeiten
Belongs to the group II decarboxylase family.
Western Blot - Anti-GAD67 Antibody (A14262) - Antibodies.com
(5)
Western Blot - Anti-GAD1 Antibody (A82616) - Antibodies.com
(2)
Immunohistochemistry - Anti-GAD67 Antibody [GAD1/2391] - BSA and Azide free (A251856) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-GAD1 Antibody (C0199) - Antibodies.com
(2)
Produkt anzeigen10µg Versuchsgrößen
Immunohistochemistry - Anti-GAD67 Antibody [GAD1/2391] (A248674) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Protein Array - Anti-GAD67 Antibody [GAD1/2563] - BSA and Azide free (A251856) - Antibodies.com
(3)
Produkt anzeigenMonospezifischer Antikörper
Protein Array - Anti-GAD67 Antibody [GAD1/2563] (A248674) - Antibodies.com
(3)
Produkt anzeigenMonospezifischer Antikörper
Western Blot - Anti-GAD67 Antibody [ARC1879] (A307047) - Antibodies.com
(2)
Western Blot - Anti-GAD1 Antibody (A82811) - Antibodies.com
Immunohistochemistry - GAD67 Antibody from Signalway Antibody (33379) - Antibodies.com
(3)
Anti-GAD-67 (A492) Antibody from Bioworld Technology (BS1135) - Antibodies.com
(2)
Western blot - GAD1/2 Antibody from Signalway Antibody (33381) - Antibodies.com
(2)
Western blot - GAD67 (GAD1) Antibody from Signalway Antibody (21624) - Antibodies.com
GAD67 antibody from Signalway Antibody (22998) - Antibodies.com
(2)
Western blot - GAD1 antibody from Signalway Antibody (38501) - Antibodies.com
GAD1 Antibody from Signalway Antibody (36878) - Antibodies.com

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