Fatty Acid Synthase ist ein Gen, das durch das Symbol FASN kodiert wird. Andere Namen sind: FASN; FAS. Fatty Acid Synthase hat eine Masse von 273.43kDa und eine Aminosäurelänge von 2511.
Wir bieten 11 antikörper gegen Fatty Acid Synthase, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC, ELISA, ICC/IF and IP mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.
Entrez Zusammenfassung
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Gewebespezifität
Ubiquitous. Prominent expression in brain, lung, and liver.
Zellort
Cytoplasm. Melanosome.
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
