EDG3 ist ein Gen, das durch das Symbol S1PR3 kodiert wird. Andere Namen sind: Sphingosine 1-phosphate receptor 3; S1P receptor 3; Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3; S1PR3. EDG3 hat eine Masse von 42.25kDa und eine Aminosäurelänge von 378.
Wir bieten 5 antikörper gegen EDG3, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
Entrez Zusammenfassung
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.
Gewebespezifität
Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.
Sequenzähnlichkeiten
Belongs to the G-protein coupled receptor 1 family.
