+1 (314) 370-6046 oderKontakt

Anti-Desmocollin 2 Antikörper

6 Products

Desmocollin 2 ist ein Gen, das durch das Symbol DSC2 kodiert wird. Andere Namen sind: Desmocollin-2; Cadherin family member 2; Desmocollin-3; Desmosomal glycoprotein II; Desmosomal glycoprotein III; DSC2; CDHF2; DSC3. Desmocollin 2 hat eine Masse von 99.96kDa, eine Aminosäurelänge von 901, und ist an Arrhythmogenic right ventricular dysplasia, familial, 11 beteiligt.

Wir bieten 6 antikörper gegen Desmocollin 2, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA, ICC/IF and FC mit Proben abgeleitet von Human, Maus und Ratte.

Gen- und Proteininformationen

UniProt Zusammenfassung
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Entrez Zusammenfassung
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
Gewebespezifität
Expressed in epithelia, myocardium and lymph nodes.
Rolle bei Krankheiten
Arrhythmogenic right ventricular dysplasia, familial, 11: A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias.
Zellort
Cell membrane. Cell junction > Desmosome.
Immunohistochemistry - Anti-Desmocollin 2 Antibody [7G6] - BSA and Azide free (A251536) - Antibodies.com
(3)
Immunohistochemistry - Anti-Desmocollin 2 Antibody [7G6] (A248354) - Antibodies.com
(3)
SDS-PAGE - Anti-Desmocollin 2 Antibody [rDSC2/3437] - BSA and Azide free (A251536) - Antibodies.com
Produkt anzeigenRekombinant Antikörper
SDS-PAGE - Anti-Desmocollin 2 Antibody [rDSC2/3437] (A248354) - Antibodies.com
Produkt anzeigenRekombinant Antikörper
Western Blot - Anti-Desmocollin 2 Antibody (A8554) - Antibodies.com
Desmocollin 2 antibody from Signalway Antibody (22014) - Antibodies.com
(2)

Zeigt 1-6 von 6 Produkten

Suchfilter Hauptmenü Kontakt 0Kasse
Oben