Cytochrome C ist ein Gen, das durch das Symbol CYCS kodiert wird. Andere Namen sind: CYCS; CYC. Cytochrome C hat eine Masse von 11.75kDa, eine Aminosäurelänge von 105, und ist an Thrombocytopenia 4 beteiligt.
Wir bieten 30 antikörper gegen Cytochrome C, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC, IP and Dot mit Proben abgeleitet von Human, Maus, Ratte, Rind, Huhn, Hund, Drosophila und Pferd.
Gen- und Proteininformationen
UniProt Zusammenfassung
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Entrez Zusammenfassung
This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
Rolle bei Krankheiten
Thrombocytopenia 4: Thrombocytopenia is defined by a decrease in the number of platelets in circulating blood, resulting in the potential for increased bleeding and decreased ability for clotting.
Sequenzähnlichkeiten
Belongs to the cytochrome c family.
Posttranslationale Modifikation
Binds 1 heme group per subunit.
Zellort
Mitochondrion intermembrane space.
Loosely associated with the inner membrane.
