CTGF ist ein Gen, das durch das Symbol CCN2 kodiert wird. Andere Namen sind: CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; CCN2; HCS24; IGFBP8. CTGF hat eine Masse von 38.09kDa und eine Aminosäurelänge von 349.
Wir bieten 20 antikörper gegen CTGF, aufgewachsen in Kaninchen, Maus, Ziege und Human, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC and IP mit Proben abgeleitet von Human, Maus, Ratte und Kaninchen.
Gen- und Proteininformationen
UniProt Zusammenfassung
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Entrez Zusammenfassung
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.
Gewebespezifität
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Sequenzähnlichkeiten
Belongs to the CCN family.
Zellort
Secreted > Extracellular space > Extracellular matrix. Secreted.
