CPI17 alpha ist ein Gen, das durch das Symbol PPP1R14A kodiert wird. Andere Namen sind: Protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC-potentiated inhibitory protein of PP1; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI-17; PPP1R14A; CPI17; PPP1INL. CPI17 alpha hat eine Masse von 16.69kDa und eine Aminosäurelänge von 147.
Wir bieten 7 antikörper gegen CPI17 alpha, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Entrez Zusammenfassung
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gewebespezifität
Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
Sequenzähnlichkeiten
Belongs to the PP1 inhibitor family.
