Claudin 3 ist ein Gen, das durch das Symbol CLDN3 kodiert wird. Andere Namen sind: Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; Rat ventral prostate.1 protein homolog; hRVP1; CLDN3; C7orf1; CPETR2. Claudin 3 hat eine Masse von 23.32kDa und eine Aminosäurelänge von 220.
Wir bieten 13 antikörper gegen Claudin 3, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Entrez Zusammenfassung
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Sequenzähnlichkeiten
Belongs to the claudin family.
Zellort
Cell junction > Tight junction. Cell membrane.
