Claudin 2 ist ein Gen, das durch das Symbol CLDN2 kodiert wird. Andere Namen sind: Claudin-2; SP82; CLDN2. Claudin 2 hat eine Masse von 24.55kDa und eine Aminosäurelänge von 230.
Wir bieten 7 antikörper gegen Claudin 2, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Entrez Zusammenfassung
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
Sequenzähnlichkeiten
Belongs to the claudin family.
Posttranslationale Modifikation
The disulfide bond is necessary for pore formation, but is not required for correct protein trafficking.
Zellort
Cell junction > Tight junction. Cell membrane.
