CDX2 ist ein Gen, das durch das Symbol CDX2 kodiert wird. Andere Namen sind: Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2; CDX3. CDX2 hat eine Masse von 33.52kDa und eine Aminosäurelänge von 313.
Wir bieten 47 antikörper gegen CDX2, aufgewachsen in Kaninchen, Maus und Ziege, welche geeignet sind für WB, IHC, ELISA, ICC/IF and IP mit Proben abgeleitet von Human, Maus, Ratte und Affe.
Gen- und Proteininformationen
UniProt Zusammenfassung
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA (PubMed:28473536).
Entrez Zusammenfassung
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
Sequenzähnlichkeiten
Belongs to the Caudal homeobox family.
Posttranslationale Modifikation
Phosphorylation of Ser-60 mediates the transactivation capacity.
