Annexin VI ist ein Gen, das durch das Symbol ANXA6 kodiert wird. Andere Namen sind: Annexin A6; 67 kDa calelectrin; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70; ANXA6; ANX6. Annexin VI hat eine Masse von 75.87kDa und eine Aminosäurelänge von 673.
Wir bieten 14 antikörper gegen Annexin VI, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus, Ratte und Affe.
Gen- und Proteininformationen
UniProt Zusammenfassung
May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
Entrez Zusammenfassung
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
Sequenzähnlichkeiten
Belongs to the annexin family.
Posttranslationale Modifikation
Phosphorylated in response to growth factor stimulation.
Zellort
Cytoplasm. Melanosome.
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
