alpha Internexin ist ein Gen, das durch das Symbol INA kodiert wird. Andere Namen sind: Alpha-internexin; Alpha-Inx; 66 kDa neurofilament protein; NF-66; Neurofilament 5; INA; NEF5. alpha Internexin hat eine Masse von 55.39kDa und eine Aminosäurelänge von 499.
Wir bieten 9 antikörper gegen alpha Internexin, aufgewachsen in Kaninchen, Maus und Huhn, welche geeignet sind für WB, IHC and ICC/IF mit Proben abgeleitet von Human, Maus, Ratte, Rind, Schwein, Katze und Pferd.
Gen- und Proteininformationen
UniProt Zusammenfassung
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
Entrez Zusammenfassung
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.
Gewebespezifität
Found predominantly in adult CNS.
Sequenzähnlichkeiten
Belongs to the intermediate filament family.
Posttranslationale Modifikation
O-glycosylated.
