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Anti-Alpha Fodrin Antikörper

12 Products

Alpha Fodrin ist ein Gen, das durch das Symbol SPTAN1 kodiert wird. Andere Namen sind: Spectrin alpha chain, non-erythrocytic 1; Alpha-II spectrin; Fodrin alpha chain; Spectrin, non-erythroid alpha subunit; SPTAN1; NEAS; SPTA2. Alpha Fodrin hat eine Masse von 284.54kDa, eine Aminosäurelänge von 2472, und ist an Epileptic encephalopathy, early infantile, 5 beteiligt.

Wir bieten 12 antikörper gegen Alpha Fodrin, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC and ICC/IF mit Proben abgeleitet von Human, Maus, Ratte und Rind.

Gen- und Proteininformationen

UniProt Zusammenfassung
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Entrez Zusammenfassung
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
Rolle bei Krankheiten
Epileptic encephalopathy, early infantile, 5: A disorder characterized by seizures associated with hypsarrhythmia, profound mental retardation with lack of visual attention and speech development, as well as spastic quadriplegia.
Sequenzähnlichkeiten
Belongs to the spectrin family.
Posttranslationale Modifikation
Phosphorylation of Tyr-1176 decreases sensitivity to cleavage by calpain in vitro.
Zellort
Cytoplasm > Cytoskeleton. Cytoplasm > Cell cortex.

Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells.
Immunofluorescence - Anti-a-II Spectrin Antibody (A85353) - Antibodies.com
(4)
Produkt anzeigen10µl Versuchsgrößen
Immunofluorescence - Anti-a-II Spectrin Antibody (A85352) - Antibodies.com
(2)
Produkt anzeigen10µl Versuchsgrößen
Immunohistochemistry - Anti-alpha Fodrin Antibody [SPTAN1/3351] - BSA and Azide free (A253220) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha Fodrin Antibody [SPTAN1/3352] - BSA and Azide free (A253221) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha Fodrin Antibody [SPTAN1/3352] (A250041) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha II Spectrin Antibody [SPTAN1/3507] - BSA and Azide free (A278400) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha II Spectrin Antibody [SPTAN1/3506] (A277811) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha II Spectrin Antibody [SPTAN1/3507] (A277812) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha II Spectrin Antibody [SPTAN1/3505] - BSA and Azide free (A278398) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha Fodrin Antibody [SPTAN1/3351] (A250040) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha II Spectrin Antibody [SPTAN1/3506] - BSA and Azide free (A278399) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-alpha II Spectrin Antibody [SPTAN1/3505] (A277810) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper

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