AHSG ist ein Gen, das durch das Symbol AHSG kodiert wird. Andere Namen sind: Alpha-2-HS-glycoprotein; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A; FETUA. AHSG hat eine Masse von 39.34kDa, eine Aminosäurelänge von 367, und ist an Alopecia-mental retardation syndrome 1 beteiligt.
Wir bieten 8 antikörper gegen AHSG, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC and ICC/IF mit Proben abgeleitet von Human.
Gen- und Proteininformationen
UniProt Zusammenfassung
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
Entrez Zusammenfassung
The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several processes, including endocytosis, brain development, and the formation of bone tissue. Defects in this gene are a cause of susceptibility to leanness.
Gewebespezifität
Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
Rolle bei Krankheiten
Alopecia-mental retardation syndrome 1: A rare autosomal recessive form of alopecia. APMR1 patients show loss of hair on the scalp, absence of eyebrows, eyelashes, axillary and pubic hair, and mild to severe mental retardation.
Sequenzähnlichkeiten
Belongs to the fetuin family.
Posttranslationale Modifikation
Phosphorylated by FAM20C in the extracellular medium.
