ADFP ist ein Gen, das durch das Symbol PLIN2 kodiert wird. Andere Namen sind: Perilipin-2; Adipophilin; Adipose differentiation-related protein; ADRP; PLIN2. ADFP hat eine Masse von 48.08kDa und eine Aminosäurelänge von 437.
Wir bieten 17 antikörper gegen ADFP, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA, ICC/IF and FC mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
May be involved in development and maintenance of adipose tissue.
Entrez Zusammenfassung
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
Gewebespezifität
Milk lipid globules.
Sequenzähnlichkeiten
Belongs to the perilipin family.
Posttranslationale Modifikation
Acylated; primarily with C14, C16 and C18 fatty acids.
Zellort
Membrane. Lipid droplet.
