PDE1A ist ein Gen, das durch das Symbol PDE1A kodiert wird. Im Allgemeinen auch bezeichnet als: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Cam-PDE 1A; 61 kDa Cam-PDE; hCam-1. PDE1A hat eine Masse von 61.25kDa und eine Aminosäurelänge von 535.
Wir bieten 2 PDE1A ELISA-Kits zum qualitativen oder quantitativen Nachweis von PDE1A von Human proben.
Gen- und Proteininformationen
UniProt Zusammenfassung
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
Entrez Zusammenfassung
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001
Gewebespezifität
Several tissues, including brain, kidney, testes and heart.
Sequenzähnlichkeiten
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
