MCP3 ist ein Gen, das durch das Symbol CCL7 kodiert wird. Im Allgemeinen auch bezeichnet als: C-C motif chemokine 7; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; NC28; Small-inducible cytokine A7; CCL7; SCYA6; SCYA7. MCP3 hat eine Masse von 11.2kDa und eine Aminosäurelänge von 99.
Wir bieten 14 MCP3 ELISA-Kits zum qualitativen oder quantitativen Nachweis von MCP3 von Human, Maus und Ratte proben.
Gen- und Proteininformationen
UniProt Zusammenfassung
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
Entrez Zusammenfassung
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.
Sequenzähnlichkeiten
Belongs to the intercrine beta (chemokine CC) family.
Posttranslationale Modifikation
O-glycosylated.
