ICAM1 ist ein Gen, das durch das Symbol ICAM1 kodiert wird. Im Allgemeinen auch bezeichnet als: Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor. ICAM1 hat eine Masse von 57.83kDa und eine Aminosäurelänge von 532.
Wir bieten 21 ICAM1 ELISA-Kits zum qualitativen oder quantitativen Nachweis von ICAM1 von Human, Maus, Ratte, Schwein, Kaninchen und Hund proben.
Gen- und Proteininformationen
UniProt Zusammenfassung
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Entrez Zusammenfassung
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
Sequenzähnlichkeiten
Belongs to the immunoglobulin superfamily. ICAM family.
Posttranslationale Modifikation
Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
