GRO beta ist ein Gen, das durch das Symbol CXCL2 kodiert wird. Im Allgemeinen auch bezeichnet als: C-X-C motif chemokine 2; Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha; CXCL2; GRO2; GROB; MIP2A; SCYB2. GRO beta hat eine Masse von 11.39kDa und eine Aminosäurelänge von 107.
Wir bieten 2 GRO beta ELISA-Kits zum qualitativen oder quantitativen Nachweis von GRO beta von Human proben.
Gen- und Proteininformationen
UniProt Zusammenfassung
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
Entrez Zusammenfassung
This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation.
Sequenzähnlichkeiten
Belongs to the intercrine alpha (chemokine CxC) family.
Posttranslationale Modifikation
The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
