Activin A ist ein Gen, das durch das Symbol INHBA kodiert wird. Andere Namen sind: Inhibin beta A chain; Activin beta-A chain; Erythroid differentiation protein; EDF; INHBA. Activin A hat eine Masse von 47.44kDa und eine Aminosäurelänge von 426.
Wir bieten 5 Activin A ELISA-Kits zum qualitativen oder quantitativen Nachweis von Activin A von Human, Maus und Ratte proben.
Gen- und Proteininformationen
UniProt Zusammenfassung
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Entrez Zusammenfassung
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients.
Sequenzähnlichkeiten
Belongs to the TGF-beta family.
