Allgemeine Hinweise
Mouse anti Phenobarbital antibody, clone PH3 recognizes phenobarbital, one of around 12 compounds derivatised from barbituric acid. These compounds are central nervous system depressants and are commonly used as sedatives, anaesthetics, hypnotics and anticonvulsants. They can be classified into three groups: ultra-short-acting (clinically used as anaesthetics), short/intermediate-acting and long-acting (clinically used as anticonvulsants). Barbiturates are addictive and potentially very dangerous, producing feelings of tranquillity, but overdose can lead to a dramatic fall in blood pressure and body temperature, depressed respiration and coma. The short-acting barbiturates are the most favoured by recreational drug users.Phenobarbital is the most widely used anticonvulsant, often used for long-term control of seizures, since it has a very long half-life (2-7 days).