Anti-PGP9.5 Antikörper [UCHL1/4558] (A250277)

Name: Anti-PGP9.5 Antibody [UCHL1/4558]
Brand: Antibodies.com
SKU: A250277
Price: 525.0 USD
Availability: InStock

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$525

Monoklonal [UCHL1/4558] Maus Antikörper gegen PGP9.5 für WB und IHC-P.

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Carrier Free and Preservative Free

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

Kontakt

Telefon

+1 (314) 370-6046

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Stichworte:

Monospezifischer Antikörper Neuronal Marker

Produktdetails

Produktname

Anti-PGP9.5 Antibody [UCHL1/4558]

Beschreibung

Mouse monoclonal [UCHL1/4558] antibody to PGP9.5.

Spezifität

This antibody reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinsons disease.

Anwendungen

WB, IHC-P

Verdünnungen

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Reaktivität

Human, Rat

Kreuzreaktivität

This antibody is predicted to cross react with Horse, Bovine, Porcine, and Mouse based on sequence homology.

Immunogen

Synthetic peptide, around amino acids 185-214, of human UCHL1 protein, conjugated to KLH.

Wirt

Mouse

Klonalität

Monoclonal

Klon

UCHL1/4558

Isotyp

IgG1

Leichte Ketten

kappa

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

200 µg/ml

Molekulargewicht

20-30 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-PGP9.5 Antibody [UCHL1/4558] - BSA and Azide free (A253457).

Synonyme

Epididymis luminal protein 117, Epididymis secretory protein Li 53, HEL 117, HEL S 53, NDGOA, Neuron cytoplasmic protein 9.5, OTTHUMP00000218137, OTTHUMP00000218139, OTTHUMP00000218140, OTTHUMP00000218141, Park 5, PARK5, PGP 9.5, PGP95, Protein gene product 9.5, Ubiquitin C terminal esterase L1, Ubiquitin C terminal hydrolase, Ubiquitin C terminal hydrolase L1, Ubiquitin carboxyl terminal esterase L1, Ubiquitin carboxyl terminal hydrolase isozyme L1, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Ubiquitin thioesterase L1, Ubiquitin thiolesterase, Ubiquitin thiolesterase L1, UCH-L1, UCHL1, UCHL1_HUMAN

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (4)

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Figure 1: Immunohistochemistry - Anti-PGP9.5 Antibody [UCHL1/4558] (A250277)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cerebellum using Anti-PGP9.5 Antibody [UCHL1/4558].

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Figure 2: Immunohistochemistry - Anti-PGP9.5 Antibody [UCHL1/4558] (A250277)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cerebellum using Anti-PGP9.5 Antibody [UCHL1/4558].

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Figure 3: Western Blot - Anti-PGP9.5 Antibody [UCHL1/4558] (A250277)

Western blot analysis of human brain tissue and T98G cell lysates using Anti-PGP9.5 Antibody [UCHL1/4558].

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Figure 4: Anti-PGP9.5 Antibody [UCHL1/4558] (A250277)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-PGP9.5 Antibody [UCHL1/4558]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.