This antibody recognises perforin, also known as cytolysin, a cytolytic protein found in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. The importance of perforin in maintaining immune homeostasis and immune surveillance is extremely well documented. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
Anwendungen
WB
Verdünnungen
WB: 0.5 - 4.0 µg/ml
Reaktivität
Rat, Human, Mouse
Immunogen
Synthetic peptide corresponding to residues surrounding amino acid 568 of rat perforin.
Wirt
Rabbit
Klonalität
Polyclonal
Isotyp
IgG
Konjugat
Unconjugated
Konzentration
500 µg/ml
Molekulargewicht
Approximately 70 kDa in Jurkat lysates
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline with 30% Glycerol, 0.5% BSA, and 0.01% Thiomersal.
Lagerung
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Rabbit anti perforin antibody recognizes perforin, also known as cytolysin, acytolyticprotein found in the granules ofcytotoxic T lymphocytes (CTLs)andNK cells. The importance of perforin in maintaining immune homeostasis and immune surveillance is extremely well documented. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis