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Rekombinant Anti-PAX6 Antikörper [PAX6/7078R] (A278039)

Monoklonal [PAX6/7078R] Kaninchen Antikörper gegen PAX6 für Flow Cytometry, IF und WB.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-PAX6 Antibody [PAX6/7078R]
Beschreibung
Recombinant rabbit monoclonal [PAX6/7078R] antibody to PAX6.
Spezifität
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
Anwendungen
Flow Cytometry, IF, WB
Verdünnungen
Flow Cytometry: 0.5-1 µg/million cells, IF: 0.5-1 µg/ml, WB: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment corresponding to the N terminus, around amino acids 1-300, of human PAX6 protein.
Wirt
Rabbit
Klonalität
Monoclonal
Klon
PAX6/7078R
Isotyp
IgG
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
47 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-PAX6 Antibody [PAX6/7078R] - BSA and Azide free (A278627).
Synonyme
AN, AN 2, AN2, Aniridia type II protein, D11S812E, FVH1, KIAA0552, Leucine zipper putative tumor suppressor 3, LZTS3, MGC17209, MGDA, Oculorhombin, Paired box 6, Paired Box Gene 6, Paired box gene 6 (aniridia keratitis), Paired box homeotic gene 6, Paired box protein Pax-6, Paired box protein Pax6, PAX 6, PAX6_HUMAN, ProSAP-interacting protein 1, PROSAPIP1, Sey, WAGR
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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