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Anti-PAX3 Antikörper [PAX3/8426] (A315467)

$765

Monoklonal [PAX3/8426] Maus Antikörper gegen PAX3 für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-PAX3 Antibody [PAX3/8426]
Beschreibung
Mouse monoclonal [PAX3/8426] antibody to PAX3.
Spezifität
Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
Anwendungen
IHC-P
Positivkontrolle
Human skin and skeletal muscle tissue.
Verdünnungen
IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment (around Amino Acids 150-350) of human PAX3 protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
PAX3/8426
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
56 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
CDHS, HUP 2, HUP2, MGC120381, MGC120382, MGC120383, MGC120384, MGC134778, Paired box 3, Paired box gene 3, Paired box homeotic gene 3, Paired box protein Pax 3, Paired box protein Pax-3, Paired box protein Pax3, Paired domain gene 3, Paired domain gene HuP2, PAX 3, PAX3/FKHR fusion gene, PAX3_HUMAN, Sp, splotch, Waardenburg syndrome 1, WS 1, WS1, WS3
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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