Rekombinant Anti-p75 NGF Receptor Antikörper [rNGFR/8824] (A315450)

Anti-p75 NGF Receptor Antibody [rNGFR/8824]

Recombinant mouse monoclonal [rNGFR/8824] antibody to p75 NGF Receptor.

It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.

IHC-P

U87 cells. Neuronal axons, Schwann cells, and perineural cells of peripheral nerves, or tumors of nerve sheath differentiation. Human melanomas.

IHC: 1-2 µg/ml

Human

Recombinant full-length human p75 NGFR protein.

Mouse

Monoclonal

rNGFR/8824

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

75 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CD271, CD271 antigen, Gp80 LNGFR, Gp80-LNGFR, Low affinity nerve growth factor receptor, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, Nerve growth factor receptor, Nerve growth factor receptor TNFR superfamily member 16, NGF receptor, Ngfr, p75 ICD, p75 Neurotrophin receptor, p75 NTR, p75(NTR), p75NTR, TNFR Superfamily Member 16, TNFRSF16, TNR16_HUMAN, Tumor necrosis factor receptor superfamily member 16