Anti-p63 Antibody [PCRP-TP63-2G3] - BSA and Azide free (A278423)

Anti-p63 Antibody [PCRP-TP63-2G3] - BSA and Azide free

Mouse monoclonal [PCRP-TP63-2G3] antibody to p63.

p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant full-length human p63 protein.

Mouse

Monoclonal

PCRP-TP63-2G3

IgG

Protein A/G chromatography.

1 mg/ml

22 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-p63 Antibody [PCRP-TP63-2G3] (A277835).

Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, KET, p40, p51, P73H, P73L, TP63, TP73L, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like