Anti-OCT-4 Antikörper [OCT4/3508] (A277757)

Anti-OCT-4 Antibody [OCT4/3508]

Mouse monoclonal [OCT4/3508] antibody to OCT-4.

Oct4 Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Interacts with UBE2I and ZSCAN10. Interacts with PKM2. Interacts with WWP2. Transcriptional activity is positively regulated by PKM2. Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues. Belongs to the POU transcription factor family. Class- 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

IHC-P

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 1-134, of human OCT-4 protein. The exact sequence is proprietary.

Mouse

Monoclonal

OCT4/3508

IgG2b

kappa

Protein A/G chromatography.

200 µg/ml

38.6 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-OCT-4 Antibody [OCT4/3508] - BSA and Azide free (A278345).

MGC22487, Oct 3, Oct 4, Oct-3, OCT3, Oct4, Octamer binding protein 3, Octamer binding protein 4, Octamer binding transcription factor 3, Octamer binding transcription factor 4, Octamer-binding protein 3, Octamer-binding protein 4, Octamer-binding transcription factor 3, OTF 3, OTF 4, OTF-3, OTF3, OTF4, PO5F1_HUMAN, POU class 5 homeobox 1, POU domain class 5 transcription factor 1, POU domain transcription factor OCT4, POU domain, class 5, transcription factor 1, POU-type homeodomain-containing DNA-binding protein, POU5F1