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Anti-NuMA Antikörper [A73-B/D12] (A254329)

Monoklonal [A73-B/D12] Maus Antikörper gegen NuMA für Flow Cytometry, IF und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-NuMA Antibody [A73-B/D12] - BSA and Azide free
Beschreibung
Mouse monoclonal [A73-B/D12] antibody to NuMA.
Spezifität
This antibody recognizes a phosphorylated protein of 228kDa, identified as nuclear mitotic apparatus protein (NuMA). Its epitope is resistant to phosphatases. NuMA is intra-nuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200kDa during apoptosis. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 has been detected in patients with acute promyelocytic leukemia.
Anwendungen
Flow Cytometry, IF, IHC-P
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Colon carcinoma 174T cells.
Wirt
Mouse
Klonalität
Monoclonal
Klon
A73-B/D12
Isotyp
IgM
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
PEG precipitation.
Konzentration
1 mg/ml
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-NuMA Antibody [A73-B/D12] (A251052).
Synonyme
Centrophilin stabilizes mitotic spindle in mitotic cells, NMP 22, Nuclear matrix protein 22, Nuclear mitotic apparatus protein, Nuclear mitotic apparatus protein 1, NUMA 1, NuMA protein, NUMA1, NUMA1_HUMAN, SP H antigen, SP-H antigen, Structural nuclear protein
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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