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Anti-NME2 Antikörper [NME2/6434] (A315398)

$765

Monoklonal [NME2/6434] Maus Antikörper gegen NME2 für WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-NME2 Antibody [NME2/6434]
Beschreibung
Mouse monoclonal [NME2/6434] antibody to NME2.
Spezifität
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
Anwendungen
WB, IHC-P
Positivkontrolle
PC3, A549, HeLa or Jurkat cells. Ubiquitously expressed in all tissues.
Verdünnungen
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant full-length human NME2 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
NME2/6434
Isotyp
IgG2
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
17 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
C myc purine binding transcription factor PUF, C myc transcription factor, C-myc purine-binding transcription factor PUF, epididymis secretory sperm binding protein Li 155an, HEL-S-155an, Histidine protein kinase NDKB, MGC111212, MGC2212, NDK B, NDKB, NDKB_HUMAN, NDP kinase B, NDPK B, NDPKB, NM23 H2, nm23-H2, NM23B, NME/NM23 nucleoside diphosphate kinase 2, Non metastatic cells 2, protein (NM23B) expressed in, non-metastatic cells 2, protein (NM23) expressed in, Nucleoside diphosphate kinase B, Nucleotide diphosphate kinase B, PUF
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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