Anti-Neuron Specific Enolase Antikörper [ENO2/1375] (A248434)

Anti-Neuron Specific Enolase Antibody [ENO2/1375]

Mouse monoclonal [ENO2/1375] antibody to Neuron Specific Enolase.

This antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas.It it be usually employed in combination with other markers such as Synaptophysin,Chromogranin A, and Neurofilament.

WB, IHC-P

WB: 1-2 µg/ml, IHC-P: 0.2-0.4 µg/ml

Human, Mouse, Rat

Synthetic peptide, within amino acids 416-433, of human NSE gamma. The exact sequence is proprietary.

Mouse

Monoclonal

ENO2/1375

IgG2b

kappa

Protein A/G chromatography.

200 µg/ml

~50 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Neuron Specific Enolase Antibody [ENO2/1375] - BSA and Azide free (A251616).

2 phospho D glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, Eno 2, ENO2, ENOG, ENOG_HUMAN, Enolase 2, Enolase 2 (gamma, neuronal), Enolase 2 gamma neuronal, Enolase2, Epididymis secretory protein Li 279, Gamma enolase, Gamma-enolase, HEL S 279, Neural enolase, Neuron specific gamma enolase, Neuron-specific enolase, neuronal enriched enolase, Neurone specific enolase, NSE