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Anti-NCR1 Antikörper [AKS1] (A279672)

$800

Monoklonal [AKS1] Maus Antikörper gegen NCR1 für WB, Flow Cytometry, Functional Assays und IF.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-NCR1 Antibody [AKS1] - BSA and Azide free
Beschreibung
Mouse monoclonal [AKS1] antibody to NCR1.
Spezifität
This antibody recognises bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells. The bovine homologue is expressed on bovine NK cells and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells.
Anwendungen
WB, Flow Cytometry, Functional Assays, IF
Verdünnungen
Flow Cytometry: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reaktivität
Bovine, American Bison
Immunogen
Fusion protein consisting of the extracellular region of bovine CD335.
Wirt
Mouse
Klonalität
Monoclonal
Klon
AKS1
Isotyp
IgG1
Konjugat

Unconjugated

Reinigung
Protein A affinity chromatography of tissue culture supernatant.
Konzentration
1 mg/ml
Produktform
Liquid
Formulierung
Supplied in Phosphate Buffered Saline.
Lagerung
Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Allgemeine Hinweise
Mouse anti Bovine CD335 antibody, clone AKS1 recognizes bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells (Sivori et al. 1997). The bovine homologue is expressed on bovine NK cells (Storset et al. 2004) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells (Storset et al. 2004).
Synonyme
Activating NK receptor NK p46, CD335, FLJ99094, hNKp46, Ly94, Lymphocyte antigen 94, Lymphocyte antigen 94 homolog, Lymphocyte antigen 94 homolog (activating NK receptor; NK p46), Natural cytotoxicity triggering receptor 1, Natural killer cell p46-related protein, NCT1, NCTR1_HUMAN, NK cell activating receptor, NK cell-activating receptor, NK-p46, NKp46
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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