Recombinant rabbit monoclonal [NAPSA/7165R] antibody to NAPSIN A.
Spezifität
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.
Anwendungen
WB, IHC-P
Positivkontrolle
Human lung adenocarcinoma.
Verdünnungen
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment (aa50-150) of human Napsin A protein. The exact sequence is proprietary.
Wirt
Rabbit
Klonalität
Monoclonal
Klon
NAPSA/7165R
Isotyp
IgG
Leichte Ketten
kappa
Konjugat
Unconjugated
Reinigung
Protein A chromatography.
Konzentration
200 µg/ml
Molekulargewicht
37 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, Kidney derived aspartic protease like protein, NAP1, NAPA, Napsa, NAPSA_HUMAN, Napsin 1, napsin A aspartic peptidase, Napsin A precursor, Napsin-1, Napsin-A, Pronapsin A, SNAPA, TA01/TA02