Rekombinant Anti-Myogenin Antikörper [MYOG/6298R] (A278036)

Anti-Myogenin Antibody [MYOG/6298R]

Recombinant rabbit monoclonal [MYOG/6298R] antibody to Myogenin.

Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif.MyoD family members share about 80% amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms tumor.

IHC-P

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human Myogenin protein.

Rabbit

Monoclonal

MYOG/6298R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

34 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Myogenin Antibody [MYOG/6298R] - BSA and Azide free (A278624).

bHLHc3, cb553, Class C basic helix-loop-helix protein 3, MYF 4, Myf-4, MYF4, MYOG, Myogenic factor 4, Myogenic factor 4 myogenin, Myogenin myogenin factor 4, MYOG_HUMAN, OTTHUMP00000039094