Rekombinant Anti-MUC16 Antikörper [OCA125/2349R] (A250627)

Name: Anti-MUC16 Antibody [OCA125/2349R]
Brand: Antibodies.com
SKU: A250627
Price: 525.0 USD
Availability: InStock

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$525

Monoklonal [OCA125/2349R] Kaninchen Antikörper gegen MUC16 für IHC-P.

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Carrier Free and Preservative Free

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

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+1 (314) 370-6046

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Stichworte:

Rekombinant Antikörper

Produktdetails

Produktname

Anti-MUC16 Antibody [OCA125/2349R]

Beschreibung

Recombinant rabbit monoclonal [OCA125/2349R] antibody to MUC16.

Spezifität

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

Anwendungen

IHC-P

Verdünnungen

IHC-P: 1-2 µg/ml

Reaktivität

Human

Immunogen

Purified human MUC16 protein.

Wirt

Rabbit

Klonalität

Monoclonal

Klon

OCA125/2349R

Isotyp

IgG

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

200 µg/ml

Molekulargewicht

>2,000 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MUC16 Antibody [OCA125/2349R] - BSA and Azide free (A253807).

Synonyme

CA 125, CA-125, CA125, CA125 ovarian cancer antigen, Cancer antigen 125, FLJ14303, MUC 16, MUC-16, MUC16_HUMAN, Mucin 16, Mucin 16 cell surface associated, Mucin-16, Mucin16, Ovarian cancer related tumor marker CA125, Ovarian cancer-related tumor marker CA125, Ovarian carcinoma antigen CA125

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (3)

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Figure 1: Immunohistochemistry - Anti-MUC16 Antibody [OCA125/2349R] (A250627)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human ovarian carcinoma using Anti-MUC16 Antibody [OCA125/2349R].

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Figure 2: Immunohistochemistry - Anti-MUC16 Antibody [OCA125/2349R] (A250627)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human endometrial carcinoma using Anti-MUC16 Antibody [OCA125/2349R].

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Figure 3: SDS-PAGE - Anti-MUC16 Antibody [OCA125/2349R] (A250627)

SDS-PAGE analysis of Anti-MUC16 Antibody [OCA125/2349R] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.