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Anti-MICA Antikörper [MICA/4443] (A277527)

Monoklonal [MICA/4443] Maus Antikörper gegen MICA für WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-MICA Antibody [MICA/4443]
Beschreibung
Mouse monoclonal [MICA/4443] antibody to MICA.
Spezifität
MICA and MICB are stress-induced antigens that are related to major histocompatibility complex (MHC) class I molecules. MICA and MICB are frequently expressed in epithelial tumors. These highly glycosylated cell surface proteins are stably expressed without conventional class I peptide ligands or association with β-2-microglobulin. The expression is induced on proliferating or heat shock-stressed epithelial cells. MICA and MICB are broadly recognized by intestinal epithelial V L1 㠁L T cells expressing variable TCRs, suggesting that these antigens may play a central role in the signaling of cellular distress to evoke immune responses in the intestinal epithelium.
Anwendungen
WB, IHC-P
Verdünnungen
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human, Mouse, Rat
Immunogen
Recombinant fragment, around amino acids 1-200, of human MICA protein. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
MICA/4443
Isotyp
IgG2b
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
92 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MICA Antibody [MICA/4443] - BSA and Azide free (A278115).
Synonyme
FLJ36918, FLJ60820, HLA class I antigen , MGC111087, MGC21250, MHC class I chain related gene A protein, MHC class I chain related protein A, MHC class I chain related protein A HLA B HLA C, MHC class I polypeptide related sequence A, MHC class I polypeptide-related sequence A, MHC class I related protein, MIC A , MIC-A, MICA_HUMAN, OTTHUMP00000029088, OTTHUMP00000044528, OTTHUMP00000165170, OTTHUMP00000165172, PERB11.1, Stress inducible class I homolog
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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