Anti-MGMT Antibody [MGMT/8364R] (A315305)

Anti-MGMT Antibody [MGMT/8364R]

Rabbit monoclonal [MGMT/8364R] antibody to MGMT.

Cancer chemotherapeutic alkylating agents (e.g. BCNU,) act by inducing formation of lethal cross € damage it can tolerate. In normal tissues, MGMT acts as a suppressor of mutation and carcinogenesis. Tumors with high levels of MGMT are likely to be drug resistant

Jurkat or MCF-7 cells. Human tonsil or stomach (IHC).

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-100) of human MGMT. The exact sequence is proprietary.

Rabbit

Monoclonal

MGMT/8364R

IgG

Protein A/G chromatography.

200 µg/ml

21.646 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

6-O-methylguanine-DNA methyltransferase, Methylated-DNA--protein-cysteine methyltransferase, O-6-methylguanine-DNA-alkyltransferase