Rekombinant Anti-Mesothelin Antikörper [rMSLN/8764] (A315300)

Anti-Mesothelin Antibody [rMSLN/8764]

Recombinant mouse monoclonal [rMSLN/8764] antibody to Mesothelin.

Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

IHC-P

CAPAN-2 or HeLa cells. Lung Mesothelioma.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 273-407) of human Mesothelin (MSLN) protein. The exact sequence is proprietary.

Mouse

Monoclonal

rMSLN/8764

IgG2b

Unconjugated

Protein A/G chromatography.

200 µg/ml

40 kDa (Mature form) / 69 kDa (Precursor)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CAK 1, CAK1, CAK1 antigen, cleaved form, Megakaryocyte potentiating factor, Mesothelin isoform 1 precursor, MPF, Msln, MSLN_HUMAN, Pre pro megakaryocyte potentiating factor, Pre-pro-megakaryocyte-potentiating factor, SMR, SMRP, Soluble MPF mesothelin related protein