Rabbit polyclonal antibody to MEK2 (phospho Thr394).
Specificity
This antibody recognises MAPK/ERK kinase 2 (MEK 2), also known as dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2 (MAPKK 2) and ERK activator kinase 2, when phosphorylated at threonine 394.MEK 2 is a dual specificity protein kinase and a member of the MAP kinase family. MEK 2 plays a critical role in mitogen growth factor signal transduction.MEK 2 is phosphorylated at threonine 394 by CDK5.
Applications
WB, IHC-P
Dilutions
IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000
Reactivity
Human, Mouse, Rat
Immunogen
Phospho-specific peptide corresponding to residues surrounding Thr394 of human MEK 2.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti MEK 2 (pThr394) antibody recognizes MAPK/ERK kinase 2 (MEK 2), also known as dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2 (MAPKK 2) and ERK activator kinase 2, when phosphorylated at threonine 394.MEK 2 is a dual specificity protein kinase and a member of the MAP kinase family. MEK 2 plays a critical role in mitogen growth factor signal transduction.MEK 2 is phosphorylated at threonine 394 by CDK5 (Banks et al. 2015).
